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__NOTOC__ :''Glomus tumor was also the name formerly (and incorrectly) used for a tumor now called a paraganglioma.'' A glomus tumor (also known as a "solitary glomus tumor,"〔 "solid glomus tumor," or glomangioma) is a rare benign neoplasm arising from the glomus body and mainly found under the nail, on the fingertip or in the foot.〔Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.〕 They account for less than 2% of all soft tissue tumors. Glomus tumors were first described by Hoyer in 1877, while the first complete clinical description was given by Masson in 1924. Histologically, glomus tumors are made up of an afferent arteriole, anastomotic vessel, and collecting venule. Glomus tumors are modified smooth muscle cells that control the thermoregulatory function of dermal glomus bodies. As stated above, these lesions should not be confused with paragangliomas, which were formerly also called glomus tumors in now-antiquated clinical usage. Glomus tumors do not arise from glomus cells, but paragangliomas do. Familial glomangiomas have been associated with a variety of deletions in the GLMN (glomulin) gene, and are inherited in an autosomal dominant manner, with incomplete penetrance.〔 ==Presentation== Glomus tumors are usually solitary and small lesions. The vast majority of are found in the distal extremities, particularly in the hand, wrist, foot, and under the fingernails.〔 They can also be found in the middle ear. They are often painful, and the pain is reproduced when the lesion is placed in cold water. These tumors tend to have a bluish discoloration, although a whitish appearance may also be noted. Elevation of the nail bed can occur. In rare cases, the tumors may present in other body areas, such as the gastric antrum or glans penis. Treatment is essentially the same. The exact incidence of glomus tumors is unknown. The multiple variant is rare, accounting for less than 10% of all cases. The probable misdiagnosis of many of these lesions as hemangiomas or venous malformations also makes an accurate assessment of incidence difficult. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Glomus tumor」の詳細全文を読む スポンサード リンク
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